SOC Drugs

# 1. Target: GSR

Drugs

Model Evidence

6 regulons containing the target(s), GSR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


2. Target: VEGFA

Drugs

Model Evidence

19 regulons containing the target(s), VEGFA are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


Drugs in GBM Trials

# 1. Target: ALDH2

Drugs

Model Evidence

2 regulons containing the target(s), ALDH2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


2. Target: FNTA,FNTB

Drugs

Model Evidence

13 regulons containing the target(s), FNTA,FNTB are overactive in this patient.

Hallmarks Enrichment

HALLMARK_OXIDATIVE_PHOSPHORYLATION

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


FDA Approved Drugs

# 1. Target: PLA2G2A,PLA2G5

Drugs

Model Evidence

8 regulons containing the target(s), PLA2G2A,PLA2G5 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


2. Target: HBB

Drugs

Model Evidence

2 regulons containing the target(s), HBB are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


3. Target: VKORC1

Drugs

Model Evidence

2 regulons containing the target(s), VKORC1 are overactive in this patient.

Hallmarks Enrichment

HALLMARK_UNFOLDED_PROTEIN_RESPONSE

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


4. Target: CA2

Drugs

Model Evidence

15 regulons containing the target(s), CA2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


5. Target: ABL1

Drugs

Model Evidence

5 regulons containing the target(s), ABL1 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


6. Target: OXTR

Drugs

Model Evidence

11 regulons containing the target(s), OXTR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


7. Target: RTN4

Drugs

Model Evidence

3 regulons containing the target(s), RTN4 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


8. Target: LOXL2

Drugs

Model Evidence

1 regulons containing the target(s), LOXL2 are overactive in this patient.

Hallmarks Enrichment

HALLMARK_UNFOLDED_PROTEIN_RESPONSE

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


9. Target: BSG

Drugs

Model Evidence

2 regulons containing the target(s), BSG are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


10. Target: NDUFA13

Drugs

Model Evidence

5 regulons containing the target(s), NDUFA13 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


11. Target: TSG101

Drugs

Model Evidence

2 regulons containing the target(s), TSG101 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


12. Target: RPS6KB1

Drugs

Model Evidence

1 regulons containing the target(s), RPS6KB1 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


13. Target: NQO1

Drugs

Model Evidence

2 regulons containing the target(s), NQO1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


14. Target: PLA2G2A

Drugs

Model Evidence

2 regulons containing the target(s), PLA2G2A are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


15. Target: TRPV4

Drugs

Model Evidence

1 regulons containing the target(s), TRPV4 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


16. Target: MAPK1,MAPK3

Drugs

Model Evidence

19 regulons containing the target(s), MAPK1,MAPK3 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


17. Target: ABAT

Drugs

Model Evidence

16 regulons containing the target(s), ABAT are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


18. Target: TNFRSF1A

Drugs

Model Evidence

15 regulons containing the target(s), TNFRSF1A are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


19. Target: EEF2

Drugs

Model Evidence

10 regulons containing the target(s), EEF2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


20. Target: HSPA8

Drugs

Model Evidence

27 regulons containing the target(s), HSPA8 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


21. Target: HRH1

Drugs

Model Evidence

43 regulons containing the target(s), HRH1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


22. Target: CA12,CA2,CA4

Drugs

Model Evidence

24 regulons containing the target(s), CA12,CA2,CA4 are overactive in this patient.

Hallmarks Enrichment

HALLMARK_HYPOXIA

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


23. Target: CA2,CA4

Drugs

Model Evidence

15 regulons containing the target(s), CA2,CA4 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


24. Target: APP

Drugs

Model Evidence

36 regulons containing the target(s), APP are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


25. Target: SLC6A9

Drugs

Model Evidence

13 regulons containing the target(s), SLC6A9 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


26. Target: FNTA,FNTB

Drugs

Model Evidence

13 regulons containing the target(s), FNTA,FNTB are overactive in this patient.

Hallmarks Enrichment

HALLMARK_OXIDATIVE_PHOSPHORYLATION

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


27. Target: HRH1,SLC6A2

Drugs

Model Evidence

43 regulons containing the target(s), HRH1,SLC6A2 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


28. Target: GSR

Drugs

Model Evidence

6 regulons containing the target(s), GSR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


29. Target: JAK2

Drugs

Model Evidence

17 regulons containing the target(s), JAK2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


30. Target: SOD1

Drugs

Model Evidence

5 regulons containing the target(s), SOD1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


31. Target: ACVR2B

Drugs

Model Evidence

5 regulons containing the target(s), ACVR2B are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


32. Target: VEGFA

Drugs

Model Evidence

19 regulons containing the target(s), VEGFA are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


33. Target: UGCG

Drugs

Model Evidence

41 regulons containing the target(s), UGCG are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots

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